Luminal esophageal temperature rise and esophageal lesion formation following remote-controlled magnetic pulmonary vein isolation

Abstract

Background: Remote magnetic pulmonary vein isolation (PVI) demonstrates comparable success rate to manual ablation, but thermal effects on esophageal tissue remain undefined.

Objective: The purpose of this study was to evaluate the potential thermal effects on esophageal tissue during remote magnetic wide-area circumferential pulmonary vein isolation (CPVI).

Methods: Twenty-five patients (23 men, age 57 ± 10 years) in the magnetic navigation system (MNS) group and 25 control subjects (15 men, age 61 ± 12 years) with drug-refractory paroxysmal or persistent atrial fibrillation underwent CPVI. A magnetic 3.5-mm irrigated-tip catheter (NaviStar ThermoCool RMT, Biosense Webster) and a nonmagnetic 3.5-mm irrigated-tip catheter (NaviStar ThermoCool, Biosense Webster) were used in the MNS and control group, respectively. A temperature probe (SensiTherm, St. Jude Medical), containing 3 thermocouples was placed in close proximity to the ablation site monitoring luminal esophageal temperature (LET). LET changes did not guide therapy. Postprocedural esophagogastroduodenoscopy (EGD) was performed in all patients.

Results: Successful CPVI was achieved in all patients. No esophageal lesions, minimal lesions, or ulcerations were found in 16 of 25 (64%), 7 of 25 (28%), and 2 of 25 (8%) in the MNS group and in 14 of 25 (56%), 10 of 25 (40%), and 1 of 25 (4%) patients in the control group, respectively. No atrioesophageal fistula occurred. Mean maximum LET in the magnetic group was 43.7°C ± 3.7°C compared to 45.4°C ± 3.5°C in the manual control group (P = .09).

Conclusion: Remote magnetic PVI is associated with significant rise in LET and development of thermal esophageal lesions. In the MNS group, higher LET recordings were more likely to cause esophageal injury, whereas this association was not seen in the manual group despite a tendency toward higher mean maximum LET recordings.