Circulating coxsackievirus A16 identified as recombinant type A human enterovirus, China

Emerg Infect Dis. 2011 Aug;17(8):1537-40. doi: 10.3201/eid1708.101719.

Abstract

To determine the relationship of coxsackievirus A16 (CA16) to prototype CA16-G10, we conducted a phylogenetic analysis of circulating CA16 strains in China. Complex recombinant forms of CA16-related viruses involving multiple human enteroviruses, subgroup A (CA4, CA16, and enterovirus 71), are prevalent among patients with hand, foot, and mouth disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • China / epidemiology
  • Enterovirus A, Human / classification
  • Enterovirus A, Human / genetics*
  • Enterovirus Infections / epidemiology*
  • Enterovirus Infections / virology
  • Hand, Foot and Mouth Disease / epidemiology*
  • Hand, Foot and Mouth Disease / virology
  • Humans
  • Molecular Sequence Data
  • Phylogeny*
  • Recombination, Genetic*
  • Sequence Analysis, DNA

Associated data

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  • GENBANK/HQ450560
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  • GENBANK/HQ450582