Nanoparticles of the novel coordination polymer KBi(H2O)2[Fe(CN)6]·H2O as a potential contrast agent for computed tomography

Inorg Chem. 2011 Sep 5;50(17):7910-2. doi: 10.1021/ic200587s. Epub 2011 Jul 28.

Abstract

An aqueous synthetic procedure for preparing nanoparticles of the novel potassium bismuth ferrocyanide coordination polymer KBi(H(2)O)(2)[Fe(CN)(6)]·H(2)O is reported. The crystal structure of this coordination polymer is determined through X-ray powder diffraction using the bulk materials. The stability, cytotoxicity, and potential use of such nanoparticles coated with PVP as a CT contrast agent are investigated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bismuth / chemistry
  • Bismuth / pharmacology
  • Cell Survival / drug effects
  • Contrast Media / chemical synthesis*
  • Contrast Media / chemistry
  • Dose-Response Relationship, Drug
  • Ferrocyanides / chemistry
  • Ferrocyanides / pharmacology
  • HeLa Cells
  • Humans
  • Models, Molecular
  • Nanoparticles / chemistry*
  • Particle Size
  • Polyvinyls / chemistry
  • Potassium / chemistry
  • Powder Diffraction
  • Pyrrolidines / chemistry
  • Surface Properties
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media
  • Ferrocyanides
  • Polyvinyls
  • Pyrrolidines
  • poly(N-vinylpyrrolidine)
  • Potassium
  • Bismuth