[Efficacy of adalimumab in Behçet's disease. Description of 6 cases]

Reumatol Clin. 2011 Jul-Aug;7(4):258-61. doi: 10.1016/j.reuma.2010.10.003. Epub 2011 Feb 18.
[Article in Spanish]

Abstract

Behçet's disease (BD) is a systemic vasculitis, with a more aggressive course in young males. Orogenital ulcers, uveitis and cutaneous lesions are the most frequent manifestations. We analyzed the effects of adalimumab on six patients with BD pretreated with inmunosupressive therapy, two of whom had received infliximab. We observed a good clinical response in all patients. To date, after a mean follow-up of 26.8 months, patients continue receiving adalimumab, with good clinical control, no adverse effects have been reported with adalimumab.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adalimumab
  • Adult
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Behcet Syndrome / drug therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*

Substances

  • Antibodies, Monoclonal, Humanized
  • Tumor Necrosis Factor-alpha
  • Adalimumab