[Diffuse alveolar hemorrhage: Causes and outcomes in a referral center]

Ivette Buendía-Roldán; Carmen Navarro; Jorge Rojas-Serrano

doi:10.1016/j.reuma.2009.07.010

[Diffuse alveolar hemorrhage: Causes and outcomes in a referral center]

Reumatol Clin. 2010 Jul-Aug;6(4):196-8. doi: 10.1016/j.reuma.2009.07.010. Epub 2010 Apr 27.

[Article in Spanish]

Authors

Ivette Buendía-Roldán¹, Carmen Navarro, Jorge Rojas-Serrano

Affiliation

¹ Instituto Nacional de Enfermedades Respiratorias Dr. Ismael Cosio Villegas, Facultad de Medicina, Universidad Nacional Autónoma de México, México.

PMID: 21794712
DOI: 10.1016/j.reuma.2009.07.010

Abstract

Objective: To identify the most common causes of diffuse alveolar hemorrhage (DAH) and the evolution of cases during hospitalization.

Patients and methods: A review of cases diagnosed with DAH; the diagnoses were classified according to existing criteria and the progression of the cases was determined.

Results: We identified 17 cases of DAH, with the leading cause being ANCA associated vasculitis (41% of cases), followed by cases secondary to drugs (18%). In 35% of the cases, there was a failure in identifying an etiology. Six patients died (35%), the only factor associated with mortality was male gender 5/6 vs 3/11, p=0.05.

Conclusions: The most frequent cause of alveolar hemorrhage was ANCA associated vasculitis. The mortality in DAH is about 35%, males seem to have a worse prognosis.

Publication types

English Abstract