Biochemical study of dermatan sulfate glycosaminoglycan in adult male patients with Nyhus type II inguinal hernia

Rev Col Bras Cir. 2011 May-Jun;38(3):167-71. doi: 10.1590/s0100-69912011000300005.
[Article in English, Portuguese]

Abstract

Objective: To compare the amount of the dermatan sulfate glycosaminoglycan between male patients with Nyhus type II inguinal hernias and subjects without inguinal hernia, aged between 20 and 40 years.

Methods: Two groups were formed: One with 15 male patients with Nyhus type II inguinal hernia and aged between 20 and 40 years with ASA risk I and II, and a control group of ten individuals, also males between 20 and 40, who had died up to 24 h before. We excluded female patients, diabetic patients with connective tissue disease, smokers and surgical risk ASA III and IV. We resected a sample of 1 cm² of the transversalis fascia in the middle of the inguinal trigone, and 1 cm² of the anterior sheath of the rectus abdominis muscle in the groin for the quantification of dermatan sulfate glycosaminoglycans by densitometry after agarose gel electrophoresis.

Results: The amount of dermatan sulfate showed no statistically significant difference between patients with inguinal hernia and individuals without inguinal hernia in both the transverse fascia (p = 0.108) and anterior sheath of the rectus abdominis muscle (p = 0.292).

Conclusion: There was no difference in the amount of the dermatan sulfate glycosaminoglycan among patients with Nyhus type II inguinal hernias and subjects without inguinal hernia in adult males.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Dermatan Sulfate / analysis*
  • Fascia / chemistry*
  • Hernia, Inguinal / classification*
  • Humans
  • Male
  • Rectus Abdominis / chemistry*
  • Young Adult

Substances

  • Dermatan Sulfate