Risk assessment induced by knapsack or conventional motor sprayer on pesticides applicators and farm workers in cotton season

Manal E A Elhalwagy; Hoda E A Farid; Farag A A Gh; Abd Elmegeed Ammar; Gamila A M Kotb

doi:10.1016/j.etap.2010.04.004

Risk assessment induced by knapsack or conventional motor sprayer on pesticides applicators and farm workers in cotton season

Environ Toxicol Pharmacol. 2010 Sep;30(2):110-5. doi: 10.1016/j.etap.2010.04.004. Epub 2010 Apr 28.

Authors

Manal E A Elhalwagy¹, Hoda E A Farid, Farag A A Gh, Abd Elmegeed Ammar, Gamila A M Kotb

Affiliation

¹ Mammalian and Aquatic Toxicology Department, Central Agricultural Pesticide Laboratory, Agriculture Research Center, Giza 12618, Egypt.

PMID: 21787639
DOI: 10.1016/j.etap.2010.04.004

Abstract

Fakous Province in the Sharkia Governorate constitutes one of the largest agricultural areas in Egypt. The majority of people in this province rely on subsistence agriculture. In the cotton cultivation season the continuous application of pesticides is commonly used to increase agricultural productivity, using different types of spraying equipment. In this study a cohort of 210 intensive agricultural pesticide applicators and farm workers from Sawada and Akyad Elkepplia villages in Fakous Province were assessed according to the type of spraying equipment they used. Conventional motor (300l/feddan or 0.42ha) and knapsack motor sprayer (20l/feddan) were commonly used by farmers. Contamination on applicators was detected on head, body (thorax/abdomen) and legs at different percentages according to the spraying tools. The recorded results revealed that contamination with pesticides due to knapsack motor sprayers 0.76% on head, 4.8% on body and 5.8% on legs; however, conventional motor sprayers induce contamination of 3.6% on head, 23.7% on body and 29.1% on legs. Several criteria for estimating pesticide contamination by previous delivery systems were used. The most important reference biomarker was serum acetyl cholinesterase (AchE) depression. Sprayers showed changes in serum glucose levels as well as reduced erythrocytic glutathione levels (GSH). However, an increase in both total serum protein and albumin was recorded also, alongside elevation in lipid peroxidation biomarker malondialdehyde (MDA). Changes in serum biochemistry regarding enzymes reflecting cytotoxicity were also recorded, such as inhibition of alanine aminotransferase (ALT) and glutathione-S-transferase (GST). An increase in aspartate aminotransferase (AST) and glutathione reductase (GR) was observed particularly in conventional motor sprayers. Changes in enzymes activities found in this study are linked to the adverse health effects related to chronic pesticide toxicity that may lead to pathophysiological diseases, cancer or neurodegenerative disorders, which warrants further investigation.