Five-year experience of quality control for a 3D LSO-based whole-body PET scanner: results and considerations

Phys Med. 2012 Jul;28(3):210-20. doi: 10.1016/j.ejmp.2011.07.002. Epub 2011 Jul 23.

Abstract

PET scanners require routine monitoring and quality control (QC) to ensure proper scanner performance. QC helps to ensure that PET equipment performs as specified by the manufacturer and that there have not been significant changes in the system response since acceptance. In this work we describe the maintenance history and we report on the results obtained from the PET system QC testing program over 5 years at two centers, both utilizing a Siemens Biograph 16 HiRez PET/CT system. QC testing programs were based on international standards and included the manufacturer's daily QC, monthly uniformity and sensitivity, quarterly cross-calibration and annual resolution and image quality. For the Winnipeg and Novara sites, two and one PET detector blocks have been replaced, respectively. Neither system has had other significant PET system related hardware replacements. The manufacturer's suggested daily QC was sensitive to detecting problems in the function of PET detector elements. The same test was not sensitive for detecting long term drifts in the systems: the Novara system observed a significant deterioration over five years of testing in the sensitivity which exhibited a decrease of 16% as compared to its initial value measured at system installation. The measure of the energy spectrum, showed that the 511 keV photopeak had shifted to a position of 468 keV. This shift was corrected by having service personnel perform a complete system calibration and detector block setup. We recommend including tests of system energy response and of sensitivity as part of a QC program since they can provide useful information on the actual performance of the scanner. A modification of the daily QC test by the manufacturer is suggested to monitor the long term stability of the system. Image quality and spatial resolution tests have proven to be of limited value for monitoring the system over time.

MeSH terms

  • Calibration
  • Documentation
  • Imaging, Three-Dimensional / instrumentation*
  • Imaging, Three-Dimensional / standards*
  • International Agencies / standards
  • Positron-Emission Tomography / instrumentation*
  • Positron-Emission Tomography / standards*
  • Quality Control
  • Scintillation Counting
  • Sensitivity and Specificity
  • Whole-Body Irradiation / instrumentation*
  • Whole-Body Irradiation / standards*