Detection of West Nile virus lineage 2 in mosquitoes during a human outbreak in Greece

Clin Microbiol Infect. 2011 Aug;17(8):1176-80. doi: 10.1111/j.1469-0691.2010.03438.x. Epub 2011 Jan 14.

Abstract

A human outbreak of West Nile virus (WNV) infections occurred in 2010 in central Macedonia, northern Greece. Most cases were observed close to four rivers forming a large Delta, a major Mediterranean wetland. WNV lineage 2 sequences were obtained from two pools of Culex pipiens mosquitoes trapped in sites where encephalitis cases occurred a few days before the trapping. The Greek strain showed the highest homology to Hungarian and South African strains, differing from the Russian WNV lineage 2 strain, which suggests that at least two lineage 2 strains have been introduced and established in Europe, causing severe disease to humans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Culex / virology*
  • Culicidae / virology
  • Disease Outbreaks*
  • Greece / epidemiology
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Rivers
  • Sequence Analysis, DNA
  • West Nile Fever / epidemiology*
  • West Nile Fever / virology
  • West Nile virus / classification
  • West Nile virus / genetics*
  • West Nile virus / isolation & purification*
  • Wetlands

Associated data

  • GENBANK/HQ230576