Adhesive microarrays for multipurpose diagnostic tools

Lab Chip. 2011 Sep 7;11(17):3006-10. doi: 10.1039/c1lc20246d. Epub 2011 Jul 20.

Abstract

We are reporting here a new technology for the straightforward production of integrated microarrays. The approach is based on the use of adhesive supports enabling (i) the immobilization of biomolecules as microarrays (up to 2500 spots per cm(2)) and (ii) the easy assembly of these microarrays with complex 3D structures such as 96-well bottomless microplates or polymer and glass microfluidic networks. The analytical performances of the system were demonstrated for sandwich protein detection (C-reactive protein) and hybridization assays, both in classical 96-well microplate format and microfluidic environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • C-Reactive Protein / analysis
  • Glass / chemistry
  • Microfluidic Analytical Techniques / instrumentation
  • Microfluidic Analytical Techniques / methods
  • Oligonucleotide Array Sequence Analysis / instrumentation
  • Oligonucleotide Array Sequence Analysis / methods
  • Polymers / chemistry
  • Protein Array Analysis / instrumentation*
  • Protein Array Analysis / methods

Substances

  • Polymers
  • C-Reactive Protein