Abstract
Reduction of the natural sesquiterpene lactones furanoheliangolides with Stryker's reagent is an effective process for producing eremantholides through a biomimetic pathway. Other reduction products are also formed. Oxygenated functions at C-15 of the furanoheliangolide produce an increase in the velocities of the reactions and reduce the chemoselectivity of the reagent.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
4-Butyrolactone / analogs & derivatives*
-
4-Butyrolactone / chemical synthesis
-
Biomimetics
-
Bridged-Ring Compounds / chemistry*
-
Furans / chemistry*
-
Lactones / chemistry
-
Oxidation-Reduction
-
Sesquiterpenes / chemistry
-
Sesterterpenes
Substances
-
Bridged-Ring Compounds
-
Furans
-
Lactones
-
Sesquiterpenes
-
Sesterterpenes
-
furanoheliangolide
-
eremantholide
-
4-Butyrolactone