Development of a ratiometric fluorescent sensor for ratiometric imaging of endogenously produced nitric oxide in macrophage cells

Lin Yuan; Weiying Lin; Yinan Xie; Bin Chen; Jizeng Song

doi:10.1039/c1cc13047a

Development of a ratiometric fluorescent sensor for ratiometric imaging of endogenously produced nitric oxide in macrophage cells

Chem Commun (Camb). 2011 Sep 7;47(33):9372-4. doi: 10.1039/c1cc13047a. Epub 2011 Jul 18.

Authors

Lin Yuan¹, Weiying Lin, Yinan Xie, Bin Chen, Jizeng Song

Affiliation

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, PR China.

PMID: 21766113
DOI: 10.1039/c1cc13047a

Abstract

We described the development of Cou-Rho-NO as the first small-molecule suitable for ratiometric fluorescent imaging of endogenously produced nitric oxide in macrophage cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Fluorescent Dyes / chemistry*
HeLa Cells
Humans
Macrophages / metabolism*
Mice
Microscopy, Fluorescence
Nitric Oxide / metabolism*

Substances

Fluorescent Dyes
Nitric Oxide