Transpupillary thermotherapy for circumscribed choroidal hemangioma: clinical profile and treatment outcome

Ophthalmic Surg Lasers Imaging. 2011 Sep-Oct;42(5):360-8. doi: 10.3928/15428877-20110707-01. Epub 2011 Jul 14.

Abstract

Background and objective: To report the outcome of treating circumscribed choroidal hemangioma (CCH) using transpupillary thermotherapy (TTT).

Patients and methods: An infrared diode laser was used at 810 nm with a median spot size of 2.5 mm, power of 550 mW, and duration of 6.5 minutes; the median number of sittings was two. TTT spared the center of the macula when CCH involved the fovea.

Results: The mean age was 36 years (range: 13 to 63 years). CCH was subfoveal in 37.5% of the eyes and exudative retinal detachment was evident in all eyes. The tumor dimensions included thickness (median: 4.05 mm; range: 2.2 to 9.1 mm), horizontal diameter (median: 11 mm; range: 6 to 17.7 mm), and vertical diameter (median: 9.4 mm; range: 5.9 to 15.8 mm). After TTT, visual acuity improved in 44%, was maintained in 37%, and worsened in 19% of eyes. Likewise, tumor regression was achieved in thickness, vertical, and horizontal diameter in proportion of 20%, 15%, and 11%, respectively. The exudative retinal detachment resolved in 94% of eyes at the last follow-up. The median follow-up was 9.5 months.

Conclusion: Macula-sparing TTT was effective in causing regression of CCH and resorption of associated exudative retinal detachment, and helped in preserving or improving vision in 81% of treated eyes.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Choroid Neoplasms / pathology
  • Choroid Neoplasms / therapy*
  • Exudates and Transudates
  • Female
  • Follow-Up Studies
  • Hemangioma / pathology
  • Hemangioma / therapy*
  • Humans
  • Hyperthermia, Induced / methods*
  • Lasers, Semiconductor / therapeutic use
  • Macula Lutea / pathology
  • Male
  • Middle Aged
  • Retinal Detachment / diagnosis
  • Retinal Detachment / therapy
  • Treatment Outcome
  • Visual Acuity
  • Young Adult