Lower cardiorespiratory fitness in children with Type 1 diabetes

Diabet Med. 2011 Aug;28(8):1005-7. doi: 10.1111/j.1464-5491.2011.03271.x.

Abstract

Aims: The present study aimed to compare cardiorespiratory fitness levels in children with and without Type 1 diabetes. In addition, the relationship between cardiorespiratory fitness and a range of physical and clinical factors was investigated.

Methods: Eighty-eight children with Type 1 diabetes aged 5-14 years completed a submaximal step test of cardiorespiratory fitness. Sixty-two of these children were successfully matched to control subjects without diabetes based on age, sex and anthropometrics for comparison. In addition, the relationship between cardiorespiratory fitness and a range of physical and clinical variables was assessed in the children with diabetes.

Results: The heart rate response to exercise was higher in children with Type 1 diabetes, indicating reduced cardiorespiratory fitness levels compared with control subjects. Both gender and glycaemic control (HbA(1c) ) were significantly associated with cardiorespiratory fitness, with female sex and poorer glycaemic control associated with reduced fitness.

Conclusions: Future research should investigate whether the reduced fitness in children with Type 1 diabetes is attributable to lower physical activity levels, or physiological changes resulting from the diabetes pathology itself.

MeSH terms

  • Adolescent
  • Australia
  • Blood Glucose / metabolism*
  • Child
  • Child, Preschool
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Female
  • Heart Rate / physiology*
  • Humans
  • Male
  • Motor Activity / physiology*
  • Physical Fitness / physiology*
  • Risk Factors

Substances

  • Blood Glucose