Modeling and phylogeny analysis of bread wheat MnSOD

Bioinformation. 2011;6(6):209-11. doi: 10.6026/97320630006209. Epub 2011 Jun 6.

Abstract

Superoxide dismutase (SOD) acts as first line of defense against oxidative and genetic stress. Manganese superoxide dismutase (MnSOD), found in mitochondria or peroxisomes, contains Mn(III) at the active site. Therefore, it is of interest to study MnSOD from bread wheat (a grain crop). However, a structure model is not yet solved for bread wheat MnSOD. Hence, we describe the structure model of bread wheat MnSOD developed using homology model. The model provides molecular insight to metal binding molecular function towards the understanding of oxidative stress resistance in plants. The distinction of bread wheat (a monocot) MnSOD from dicots is also shown using phylogenetic analysis.

Keywords: MnSOD; dicots; monocots; stress; structure model.