Molecular targets in the design of antifibrotic therapy in chronic liver disease

Rev Esp Enferm Dig. 2011 Jun;103(6):310-23.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Antioxidants / therapeutic use
  • Collagen / drug effects
  • Collagen / metabolism
  • Disease Progression
  • Drug Design
  • Extracellular Matrix / drug effects*
  • Extracellular Matrix / metabolism
  • Fibronectins / metabolism
  • Hepatic Stellate Cells / drug effects
  • Hepatic Stellate Cells / metabolism
  • Humans
  • Intercellular Signaling Peptides and Proteins / therapeutic use
  • Interleukin-10 / therapeutic use
  • Laminin / metabolism
  • Liver Cirrhosis / prevention & control*
  • Liver Diseases / drug therapy*
  • Liver Diseases / pathology
  • Molecular Targeted Therapy*
  • Proteoglycans / metabolism
  • Renin-Angiotensin System / physiology
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Fibronectins
  • Intercellular Signaling Peptides and Proteins
  • Laminin
  • Proteoglycans
  • Tumor Necrosis Factor-alpha
  • Interleukin-10
  • Collagen