L-Theanine: properties, synthesis and isolation from tea

J Sci Food Agric. 2011 Aug 30;91(11):1931-9. doi: 10.1002/jsfa.4373. Epub 2011 Mar 29.

Abstract

Theanine is a non-protein amino acid that occurs naturally in the tea plant (Camellia sinensis) and contributes to the favourable taste of tea. It is also associated with effects such as the enhancement of relaxation and the improvement of concentration and learning ability. It is also linked with health benefits including the prevention of certain cancers and cardiovascular disease, the promotion of weight loss and enhanced performance of the immune system. Thus, there has been a significant rise in the demand for theanine. While theanine has been chemically and biologically synthesised, techniques to isolate theanine from natural sources remain an important area of research. In this review article, the properties and health benefits of theanine are summarised and the synthesis and isolation of theanine are reviewed and discussed. Future perspectives for the isolation of theanine from natural sources are also outlined.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Anxiety Agents / chemistry
  • Anti-Anxiety Agents / isolation & purification
  • Anti-Anxiety Agents / metabolism
  • Anti-Anxiety Agents / therapeutic use
  • Antihypertensive Agents / chemistry
  • Antihypertensive Agents / isolation & purification
  • Antihypertensive Agents / metabolism
  • Antihypertensive Agents / therapeutic use
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / metabolism
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Camellia sinensis / chemistry
  • Camellia sinensis / metabolism
  • Glutamates / chemistry
  • Glutamates / isolation & purification*
  • Glutamates / metabolism
  • Glutamates / therapeutic use*
  • Humans
  • Plant Leaves / chemistry
  • Plant Roots / metabolism
  • Tea / chemistry*

Substances

  • Anti-Anxiety Agents
  • Antihypertensive Agents
  • Antineoplastic Agents, Phytogenic
  • Glutamates
  • Tea
  • theanine