A novel HLA-A allele detected by sequence-based typing: A*68:66

K Loacker; P Hörtnagl; C Grabmer; H Schennach; A Mühlbacher

doi:10.1111/j.1399-0039.2011.01722.x

A novel HLA-A allele detected by sequence-based typing: A*68:66

Tissue Antigens. 2011 Nov;78(5):397. doi: 10.1111/j.1399-0039.2011.01722.x. Epub 2011 Jul 5.

Authors

K Loacker¹, P Hörtnagl, C Grabmer, H Schennach, A Mühlbacher

Affiliation

¹ Central Institute for Blood Transfusion and Immunology, University Hospital Innsbruck, Innsbruck, Austria.

PMID: 21729008
DOI: 10.1111/j.1399-0039.2011.01722.x

Abstract

The novel allele HLA-A*68:66 differs from HLA-A*68:01: 01:01 by a synonymous single nucleotide exchange at position 102 (C→T) and three non-synonymous exchanges at position 257 (G→A), position 259 (A→G) and position 261 (C→G) in exon 2.

MeSH terms

Alleles
Base Sequence
Exons
HLA-A Antigens / genetics*
Humans
Molecular Sequence Data
Sequence Alignment
Sequence Analysis, DNA

Substances

HLA-A Antigens
HLA-A*68 antigen

Associated data

GENBANK/HQ201391