Abstract
The first total synthesis of the proposed structure of phaeosphaeride A has been achieved via six-membered-ring formation by means of an intramolecular vinyl-anion aldol reaction as the key step. This synthesis suggests a revised configurational assignment for phaeosphaeride A.
MeSH terms
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Aldehydes / chemistry
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Bridged Bicyclo Compounds, Heterocyclic / chemical synthesis*
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Fungi / chemistry
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Models, Molecular
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STAT3 Transcription Factor / antagonists & inhibitors*
Substances
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Aldehydes
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Bridged Bicyclo Compounds, Heterocyclic
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STAT3 Transcription Factor
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phaeosphaeride A
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3-hydroxybutanal