FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein

Dokl Biochem Biophys. 2011 May-Jun:438:123-6. doi: 10.1134/S1607672911030045. Epub 2011 Jul 3.

Authors

T A Shelkovnikova¹, A A Ustyugov, A P Smirnov, V I Skvortsova, V L Buchman, S O Bachurin, N N Ninkina

Affiliation

¹ Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow oblast, 142432, Russia.

PMID: 21725888
DOI: 10.1134/S1607672911030045

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amyotrophic Lateral Sclerosis / genetics*
Amyotrophic Lateral Sclerosis / metabolism
Amyotrophic Lateral Sclerosis / pathology
Cell Line
Disease Progression
Genetic Predisposition to Disease
Humans
Mutation*
RNA-Binding Protein FUS / genetics*
RNA-Binding Protein FUS / metabolism

Substances

RNA-Binding Protein FUS