Abstract
Two new prenylated C₆-C₃ compounds, cycloillicinone (1) and 4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol (2), were isolated from the twigs of Illicium anisatum, and their structures were determined by 2D-NMR methods. Cycloillicinone (1) is a unique prenylated C₆-C₃ that is appended with an additional geranyl unit. Compound 2 was found to show moderate neurite-outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 µM.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cells, Cultured
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Illicium / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Conformation
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Neurons / cytology
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Neurons / drug effects
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Phenols / chemistry*
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Phenols / isolation & purification
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Phenols / pharmacology
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Rats
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Terpenes / chemistry*
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Terpenes / isolation & purification
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Terpenes / pharmacology
Substances
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4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol
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Phenols
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Terpenes
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cycloillicinone