Mechanisms of gastrointestinal surgery in treatment of type 2 diabetes

Ying-chao Gu; Jian-chun Yu

doi:10.3881/j.issn.1000-503X.2011.03.011

Mechanisms of gastrointestinal surgery in treatment of type 2 diabetes

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Jun;33(3):262-4. doi: 10.3881/j.issn.1000-503X.2011.03.011.

Authors

Ying-chao Gu¹, Jian-chun Yu

Affiliation

¹ Department of General Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.

PMID: 21718607
DOI: 10.3881/j.issn.1000-503X.2011.03.011

Abstract

Type 2 diabetes can be treated by gastrointestinal surgery, but the underlying mechanism is unclear. This review summarizes the possible mechanisms which include weight loss, gastrointestinal hormones, foregut hypothesis, hindgut hypothesis, adipocytokines, and inflammatory factors.

Publication types

Review

MeSH terms

Diabetes Mellitus, Type 2 / metabolism
Diabetes Mellitus, Type 2 / physiopathology
Diabetes Mellitus, Type 2 / surgery*
Digestive System Surgical Procedures
Gastric Bypass
Gastrointestinal Hormones / metabolism
Humans
Weight Loss

Substances

Gastrointestinal Hormones