Synthesis and structure of all-syn-1,2,3,4-tetrafluorocyclohexane

Chem Commun (Camb). 2011 Aug 7;47(29):8265-7. doi: 10.1039/c1cc13016a. Epub 2011 Jun 28.

Abstract

Preparation of the all-syn isomer of 1,2,3,4-tetrafluorocyclohexane is reported; X-ray structural studies shows a conformation with two of the C-F bonds oriented 1,3-diaxial to each other and (19)F-NMR reveals a through space diaxial (4)J(FF) coupling constant of 29 Hz.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Cyclohexanes / chemical synthesis*
  • Cyclohexanes / chemistry*
  • Hydrocarbons, Fluorinated / chemical synthesis*
  • Hydrocarbons, Fluorinated / chemistry
  • Molecular Conformation
  • Stereoisomerism

Substances

  • 1,2,3,4-tetrafluorocyclohexane
  • Cyclohexanes
  • Hydrocarbons, Fluorinated
  • Cyclohexane