3.0T MR-guided laser ablation of a prostate cancer recurrence in the postsurgical prostate bed

J Vasc Interv Radiol. 2011 Jul;22(7):929-34. doi: 10.1016/j.jvir.2011.02.039.

Abstract

Biochemical recurrence of prostate cancer after definitive therapy with radical prostatectomy occurs in 25%-30% of cases. The first known case of magnetic resonance (MR) imaging-guided ablation using laser interstitial thermal therapy (LITT) for locally recurrent prostate cancer after radical prostatectomy is presented. Using 3.0T MR guidance, two laser applicators were placed via a transperineal approach. Laser ablation was performed using MR thermometry to determine the ablation endpoint and lesion coverage. Dynamic contrast-enhanced MR imaging after the procedure showed no definitive abnormal enhancement. The patient had no change in continence or potency after the procedure.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / immunology
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery*
  • Humans
  • Laser Therapy*
  • Magnetic Resonance Imaging, Interventional*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local*
  • Neoplasm Staging
  • Prostate-Specific Antigen / blood
  • Prostatectomy*
  • Prostatic Neoplasms / immunology
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery*
  • Reoperation
  • Thermography
  • Treatment Outcome

Substances

  • Prostate-Specific Antigen