Supramolecular hydrogels based on the epitope of potassium ion channels

Chem Commun (Camb). 2011 Aug 21;47(31):8772-4. doi: 10.1039/c1cc13115j. Epub 2011 Jun 24.

Abstract

Imparting aromatic-aromatic interactions to the potassium binding epitope affords a supramolecular hydrogelator that responds to the K(+) concentration by self-assembly into nanofibers of different widths and crosslinking patterns, which illustrates a simple approach to generate biomimic materials based on tunable, hierarchical self-assembly of small molecules.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Epitopes / chemistry*
  • Fluorenes / chemistry
  • Hydrogels / chemistry*
  • Nanofibers / chemistry
  • Oligopeptides / chemistry
  • Potassium / metabolism
  • Potassium Channels / chemistry*
  • Potassium Channels / metabolism

Substances

  • Epitopes
  • Fluorenes
  • Hydrogels
  • Oligopeptides
  • Potassium Channels
  • Potassium