This work investigates the production of succinic acid by immobilized A. succinogenes cells, using a bioreactor with stirred/mobile bed of biocatalysts.
Material and method: The experiments have been carried out for different sizes of biocatalysts particle, under substrate and product inhibitory effects.
Results: The results indicated that the inhibitory effects could be diminished by cells immobilization, the substrate consumption rate increasing with the increase of biocatalyst particle size. Moreover, the biocatalysts can be used for many fermentation cycles.