Structures of euglobal-G1, -G2, and -G3 from Eucalyptus grandis, three new inhibitors of Epstein-Barr virus activation

Chem Pharm Bull (Tokyo). 1990 May;38(5):1444-6. doi: 10.1248/cpb.38.1444.

Abstract

Three new euglobals with acylphloroglucinol-monoterpene structures, named euglobal -G1 (1), -G2 (2), and -G3 (3) were isolated from the chloroform extract of the juvenile leaves of Eucalyptus grandis (Myrtaceae). The structures of these new compounds were determined on the basis of their spectral data. The compounds strongly inhibited the Epstein-Barr virus activation.

MeSH terms

  • Antiviral Agents / analysis*
  • Herpesvirus 4, Human / drug effects*
  • Magnetic Resonance Spectroscopy
  • Phloroglucinol / analysis
  • Phloroglucinol / pharmacology*
  • Plants, Medicinal / analysis*
  • Terpenes / analysis
  • Terpenes / pharmacology*

Substances

  • Antiviral Agents
  • Terpenes
  • euglobal G2
  • euglobal G3
  • euglobal G1
  • Phloroglucinol