Five new diarylpropan-1-ols from Combretum yunnanense

Planta Med. 2011 Nov;77(16):1841-4. doi: 10.1055/s-0030-1271179. Epub 2011 Jun 14.

Abstract

Five new 1,3-diarylpropan-1-ols, combretol A-E (1- 5), together with one known coumarin (6) and ten known triterpenes (7-16), were isolated from Combretum yunnanense. Their structures were determined by spectroscopic investigation, including ¹H and ¹³C NMR, NOESY, HSQC, HMBC, and HRESIMS analyses. This is the first report on the occurrence of 1,3-diarylpropan-1-ols and coumarin in the Combretum genus including C. yunnanense. Also, to the best of our knowledge, 1,3-diarylpropan-1-ols are rare in nature.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • China
  • Combretum / chemistry*
  • Coumarins / chemistry
  • Coumarins / isolation & purification*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Medicine, Chinese Traditional
  • Molecular Structure
  • Plant Components, Aerial / chemistry
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • Coumarins
  • Drugs, Chinese Herbal
  • Triterpenes
  • coumarin