Ultra high molecular weight polyethylene is cytotoxic and causes oxidative stress, even when modified

Int J Immunopathol Pharmacol. 2011 Jan-Mar;24(1 Suppl 2):61-7. doi: 10.1177/03946320110241S212.

Authors

E Gazzano¹, P Bracco, A Bistolfi, E Aldieri, D Ghigo, M Boffano, L Costa, E Brach Del Prever

Affiliation

¹ Department of Genetics, Biology and Biochemistry, University of Turin, Italy.

PMID: 21669140
DOI: 10.1177/03946320110241S212

No abstract available

MeSH terms

Animals
Biocompatible Materials / chemistry*
Biocompatible Materials / toxicity*
Cell Line
Cell Lineage
Cell Survival / drug effects
Cross-Linking Reagents
Humans
L-Lactate Dehydrogenase / metabolism
Macrophages / drug effects
Mice
Molecular Weight
Monocytes / drug effects
Nitric Oxide / metabolism
Osteoclasts / drug effects
Oxidation-Reduction
Oxidative Stress / drug effects*
Polyethylenes / chemistry*
Polyethylenes / toxicity*
Reactive Oxygen Species / metabolism
Spectroscopy, Fourier Transform Infrared
Vitamin E / chemistry

Substances

Biocompatible Materials
Cross-Linking Reagents
Polyethylenes
Reactive Oxygen Species
ultra-high molecular weight polyethylene
Vitamin E
Nitric Oxide
L-Lactate Dehydrogenase