Abstract
We show that respiratory fluoroquinolone use is extremely seasonal and that fluoroquinolone use is strongly associated with influenza. In our time series model, instantaneous influenza activity was a significant predictor of use (P < .0001). Also, we estimated that reducing influenza activity by 20% would reduce prescriptions by 8%.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anti-Bacterial Agents / therapeutic use*
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Drug Utilization / statistics & numerical data
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Fluoroquinolones / therapeutic use*
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Humans
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Inappropriate Prescribing
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Influenza, Human / epidemiology*
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Regression Analysis
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Respiratory Tract Infections / drug therapy
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Respiratory Tract Infections / epidemiology
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Seasons
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United States / epidemiology
Substances
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Anti-Bacterial Agents
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Fluoroquinolones