Isolated CNS relapse in human epidermal growth factor receptor 2-positive esophagogastric cancer: effective treatment with trastuzumab after failure of surgery and radiotherapy

J Clin Oncol. 2011 Aug 10;29(23):e664-5. doi: 10.1200/JCO.2011.35.8317. Epub 2011 Jun 6.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / genetics
  • Adenocarcinoma / secondary
  • Adult
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / secondary
  • Brain Neoplasms / surgery
  • Combined Modality Therapy
  • Digestive System Surgical Procedures
  • Esophageal Neoplasms / drug therapy*
  • Esophageal Neoplasms / genetics
  • Esophageal Neoplasms / pathology
  • Esophagogastric Junction / pathology
  • Humans
  • Male
  • Receptor, ErbB-2 / genetics*
  • Salvage Therapy / methods
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / genetics
  • Stomach Neoplasms / secondary
  • Trastuzumab

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • ERBB2 protein, human
  • Receptor, ErbB-2
  • Trastuzumab