Unveiled α-neurexins take center stage

Carsten Reissner; Markus Missler

doi:10.1016/j.str.2011.05.005

Unveiled α-neurexins take center stage

Structure. 2011 Jun 8;19(6):749-50. doi: 10.1016/j.str.2011.05.005.

Authors

Carsten Reissner¹, Markus Missler

Affiliation

¹ Department of Anatomy and Molecular Neurobiology, Westfälische Wilhems-University, Münster, Germany.

PMID: 21645846
DOI: 10.1016/j.str.2011.05.005

Abstract

Neurexins are presynaptic transmembrane proteins that play an essential role in synapse function. The crystal structures of α-neurexin extracellular domains (Chen et al., 2011; Miller et al., 2011) provide important insights into their conformational freedom and their putative spatial arrangement with binding partners in the synaptic cleft.

Publication types

Comment
Research Support, Non-U.S. Gov't