Meso-scale constructed wetlands have not been commonly used for the examination of interactions and operations within differently designed wetland systems. Sixteen meso-scale constructed wetland systems (4 operations with 4 replicates each) were therefore evaluated between November 2008 and June 2010. These systems were used to examine key operations identified in the literature including hydraulic loading rates, nutrient loading rates and nutrient recycling modes. The wetlands were managed in the following modes: normal, recycling, high nutrient loading and high flow rate. The designs were such that the influents could be varied at set loading rates and concentrations. The ammonia removal rates for the meso-scale integrated constructed wetland (ICW) systems were similar to other full-scale ICW systems that have been in operation in the south-east of Ireland for the past decade. These comparable results highlight the potential cost-effectiveness of these meso-scale experimental designs for the examination of novel operations for future ICW developments.