Abstract
The molecular interactions between staphylococcal phages and host cell surfaces are poorly understood. Employing Staphylococcus aureus teichoic acid mutants, we demonstrate that wall teichoic acid (WTA), but not lipoteichoic acid, serves as a receptor for staphylococcal siphovirus and myovirus, while only the siphovirus requires glycosylated WTA.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Wall / metabolism
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Cell Wall / virology
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Glycosylation
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Mutation
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Receptors, Virus / metabolism*
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Staphylococcus Phages / physiology*
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Staphylococcus aureus / genetics
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Staphylococcus aureus / metabolism*
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Staphylococcus aureus / virology*
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Teichoic Acids / metabolism*
Substances
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Receptors, Virus
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Teichoic Acids