Endometrial Indian hedgehog expression is decreased in women with endometriosis

Fertil Steril. 2011 Jun 30;95(8):2738-41.e1-3. doi: 10.1016/j.fertnstert.2011.05.018. Epub 2011 Jun 2.

Abstract

Nuclear and cytoplasmic endometrial expression of Indian hedgehog increased from the late proliferative to mid and late secretory phases in 26 healthy volunteers compared with 30 women with endometriosis. The abnormal expression of Indian hedgehog protein in women with endometriosis suggests a resistance to P action.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Adult
  • Biopsy
  • Case-Control Studies
  • Cell Nucleus / metabolism
  • Cytoplasm / metabolism
  • Down-Regulation
  • Endometriosis / metabolism*
  • Endometrium / metabolism*
  • Female
  • Hedgehog Proteins / metabolism*
  • Humans
  • Immunohistochemistry
  • Laparoscopy
  • Maryland
  • Menstrual Cycle / metabolism

Substances

  • Hedgehog Proteins
  • IHH protein, human