Reliability of repeated cognitive assessment of dementia using a brief computerized battery

Am J Alzheimers Dis Other Demen. 2011 Jun;26(4):326-33. doi: 10.1177/1533317511411907. Epub 2011 Jun 1.

Abstract

Objective: The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types.

Method: Patients were administered the computerized battery twice with administrations approximately 2 hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference, as healthy controls (n = 23), mild cognitive impairment (n = 20), Alzheimer's disease (n = 52), dementia with Lewy Bodies ([DLB], n = 10), or frontotemporal dementia (n = 9).

Results: Minimal practice effects were evident across Cog-State test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning.

Conclusions: In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / psychology
  • Dementia / diagnosis*
  • Dementia / psychology*
  • Diagnosis, Computer-Assisted
  • Female
  • Frontotemporal Dementia / diagnosis
  • Frontotemporal Dementia / psychology
  • Humans
  • Lewy Body Disease / diagnosis
  • Lewy Body Disease / psychology
  • Male
  • Michigan
  • Middle Aged
  • Neuropsychological Tests / standards*
  • Reproducibility of Results