Deep brain stimulation of the posterior hypothalamic area in intractable short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT)

Cephalalgia. 2011 Oct;31(13):1405-8. doi: 10.1177/0333102411409070. Epub 2011 May 31.

Abstract

Background: SUNCT (short-lasting unilateral neuralgiform headache with conjunctival injection and tearing) is a rare syndrome characterized by the sudden onset of excruciating unilateral periorbital pain that is accompanied by conjunctival injection and lacrimation or further autonomic signs. Similar to patients with chronic cluster headache, Leone and Lyons showed a beneficial effect of deep brain stimulation of the posterior hypothalamic region in two patients with a chronic SUNCT.

Case: Here, we present the case of a man with a chronic SUNCT responding to deep brain stimulation of the posterior hypothalamic area.

Conclusion: This case supports the idea of a central origin of SUNCT and shows that deep brain stimulation of the hypothalamic region can be effective in the treatment of the chronic form of this rare disorder.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Analgesics / therapeutic use
  • Combined Modality Therapy
  • Comorbidity
  • Deep Brain Stimulation*
  • Diagnostic Errors
  • Diagnostic Imaging
  • Drug Resistance
  • Humans
  • Hypothalamus, Posterior* / physiopathology
  • Male
  • Recurrence
  • Remission Induction
  • SUNCT Syndrome / diagnosis
  • SUNCT Syndrome / drug therapy
  • SUNCT Syndrome / physiopathology
  • SUNCT Syndrome / therapy*
  • Trigeminal Neuralgia / diagnosis

Substances

  • Analgesics