Abstract
Rapid and highly efficient side-chain functionalization of polypeptides was achieved via combination of ring-opening polymerization of a new clickable monomer of γ-propargyl-L-glutamate N-carboxyanhydride (PLG-NCA) and thiol-yne photochemistry, which provides a convenient and universal route to prepare diverse polypeptide-based biomimetic hybrid materials.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Biomimetic Materials / chemical synthesis*
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Biomimetic Materials / chemistry*
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Glutamic Acid / chemistry
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Hydrophobic and Hydrophilic Interactions
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Kinetics
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Peptides / chemistry*
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Photochemical Processes*
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Polymerization
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Sulfhydryl Compounds / chemistry*
Substances
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Alkynes
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Peptides
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Sulfhydryl Compounds
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Glutamic Acid