Prevention of enamel demineralization after tooth bleaching by bioactive glass incorporated into toothpaste

Aust Dent J. 2011 Jun;56(2):193-200. doi: 10.1111/j.1834-7819.2011.01323.x.

Abstract

Background: The aim of this study was to determine the effects of bleaching on the structure of the enamel layer of teeth and the potential of the commercial bioactive glass NovaMin® in two different toothpastes to remineralize such regions of the enamel. Three aspects were considered: the extent and nature of the alterations in the enamel after application of the bleaching agents; the extent of remineralization after application of two commercial toothpastes containing bioactive glass; and whether or not there were differences between the toothpastes in terms of their effectiveness in promoting remineralization.

Methods: Bleaching agent based on 16% carbamide peroxide was applied to the enamel surface of freshly extracted human molars for 8 minutes, once a day for 7 days. After the bleaching cycles, the enamel surface was analysed by SEM and EDX.

Results: The results obtained in the study lead to the conclusion that application of 16% carbamide peroxide causes distinct morphological changes to the enamel surface which vary from mild to severe. Subsequent treatment with either of the toothpastes containing the bioactive glass NovaMin® resulted in the formation of a protective layer on the enamel surface, consisting of bioactive glass deposits, with only slight differences between the two brands. Application of these dentifrices also caused increases in the Ca and P content of the enamel layer, returning it to that of undamaged enamel.

Conclusions: Remineralizing toothpastes should be used after bleaching, in order to repair any damage to the mineral tissue caused by these procedures.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Calcium / analysis
  • Carbamide Peroxide
  • Dental Enamel / chemistry
  • Dental Enamel / drug effects*
  • Dental Enamel / ultrastructure
  • Glass* / chemistry
  • Humans
  • Magnesium / analysis
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Peroxides / pharmacology
  • Phosphorus / analysis
  • Silicon / analysis
  • Sodium / analysis
  • Spectrometry, X-Ray Emission
  • Time Factors
  • Tooth Bleaching / methods*
  • Tooth Bleaching Agents / pharmacology
  • Tooth Demineralization / prevention & control*
  • Tooth Remineralization / methods
  • Toothpastes / pharmacology*
  • Urea / analogs & derivatives
  • Urea / pharmacology

Substances

  • NovaMin
  • Peroxides
  • Tooth Bleaching Agents
  • Toothpastes
  • Phosphorus
  • Carbamide Peroxide
  • Urea
  • Sodium
  • Magnesium
  • Calcium
  • Silicon