Palladium-catalyzed cross-coupling of H-phosphinate esters with chloroarenes

Eric L Deal; Christelle Petit; Jean-Luc Montchamp

doi:10.1021/ol201222n

Palladium-catalyzed cross-coupling of H-phosphinate esters with chloroarenes

Org Lett. 2011 Jun 17;13(12):3270-3. doi: 10.1021/ol201222n. Epub 2011 May 25.

Authors

Eric L Deal¹, Christelle Petit, Jean-Luc Montchamp

Affiliation

¹ Department of Chemistry, Box 298860, Texas Christian University, Fort Worth, Texas 76129, USA.

PMID: 21612265
DOI: 10.1021/ol201222n

Abstract

The palladium-catalyzed cross-coupling reaction between H-phosphinate esters and chloroarenes or chloroheteroarenes is described. This reaction is the first general metal-catalyzed phosphorus-carbon bond-forming reaction between a phosphorus nucleophile and chloroarenes.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Catalysis
Esters
Hydrocarbons, Chlorinated / chemistry*
Molecular Structure
Organophosphorus Compounds / chemical synthesis*
Organophosphorus Compounds / chemistry
Palladium / chemistry*

Substances

Esters
Hydrocarbons, Chlorinated
Organophosphorus Compounds
Palladium