[Xeroderma pigmentosum: a useful model to study the relation between genomic mutations and cell transformation]

Med Sci (Paris). 2011 May;27(5):467-70. doi: 10.1051/medsci/2011275007. Epub 2011 May 25.
[Article in French]
No abstract available

Publication types

  • News

MeSH terms

  • Apoptosis
  • Cell Transformation, Neoplastic / genetics*
  • Cell Transformation, Neoplastic / metabolism
  • Cellular Senescence
  • Citric Acid Cycle / genetics
  • DNA Damage
  • DNA Repair / genetics
  • DNA, Mitochondrial / drug effects
  • DNA, Mitochondrial / genetics
  • DNA-Binding Proteins / deficiency
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology*
  • Energy Metabolism / genetics*
  • Glycolysis
  • Humans
  • Keratinocytes / metabolism
  • Keratinocytes / pathology
  • Models, Biological*
  • Neoplasms / genetics
  • Neoplasms / metabolism
  • Oxidative Phosphorylation
  • Reactive Oxygen Species / metabolism
  • Reactive Oxygen Species / toxicity
  • Xeroderma Pigmentosum / genetics*

Substances

  • DNA, Mitochondrial
  • DNA-Binding Proteins
  • Reactive Oxygen Species
  • XPC protein, human