Application of human umbilical cord blood-derived mesenchymal stem cells in disease models

World J Stem Cells. 2010 Apr 26;2(2):34-8. doi: 10.4252/wjsc.v2.i2.34.

Abstract

Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) are regarded as an alternative source of bone marrow-derived mesenchymal stem cells because collection of cord blood is less invasive than that of bone marrow. hUCB-MSCs have recently been studied for evaluation of their potential as a source of cell therapy. In this review, the general characteristics of hUCB-MSCs and their therapeutic effects on various diseases in vitro and in vivo will be discussed.

Keywords: Immune modulation; Mesenchymal stem cells; Nursing effect; Regeneration.