Organophosphorus acid anhydrolase bio-template for the synthesis of CdS quantum dots

Liang Zhao; Kerim M Gattás-Asfura; Jianmin Xu; Ravi A Patel; Anup Dadlani; Myrna Sillero-Mahinay; Marie Cushmore; Vipin K Rastogi; Saumil S Shah; Roger M Leblanc

doi:10.1039/c1cc10714c

Organophosphorus acid anhydrolase bio-template for the synthesis of CdS quantum dots

Chem Commun (Camb). 2011 Jul 7;47(25):7242-4. doi: 10.1039/c1cc10714c. Epub 2011 May 20.

Authors

Liang Zhao¹, Kerim M Gattás-Asfura, Jianmin Xu, Ravi A Patel, Anup Dadlani, Myrna Sillero-Mahinay, Marie Cushmore, Vipin K Rastogi, Saumil S Shah, Roger M Leblanc

Affiliation

¹ The Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA.

PMID: 21597641
DOI: 10.1039/c1cc10714c

Abstract

A direct conjugation of organophosphorus acid anhydrolase (OPAA) with CdS quantum dots was prepared via arrested precipitation within the enzyme matrix. The bio-conjugate was found not only to retain enzyme conformational structure but also to retain enzyme activity and be effective at detecting diisopropyl fluorophosphate (DFP) at the micro molar level.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Aryldialkylphosphatase / metabolism*
Cadmium Compounds / chemical synthesis*
Cadmium Compounds / chemistry*
Quantum Dots*
Spectrum Analysis
Sulfides / chemical synthesis*
Sulfides / chemistry*

Substances

Cadmium Compounds
Sulfides
cadmium sulfide
Aryldialkylphosphatase