A singular observation of a giant benign Brenner tumor of the ovary

Arch Gynecol Obstet. 2011 Aug;284(2):513-6. doi: 10.1007/s00404-011-1930-x. Epub 2011 May 19.

Abstract

Introduction: Brenner tumors are rare transitional cell tumors of the ovary. They are usually benign neoplasms, of solid or solid-cystic structure and small size. We describe the case of a benign, predominantly cystic Brenner tumor measuring 39 cm in diameter.

Case report: A 62-year-old woman presented to the outpatient visit complaining about vague abdominal symptoms such as constipation and meteorism. Ultrasonography and CT scan showed the presence of a voluminous cystic mass, with fluid content, displacing other intra-abdominal organs. The patient underwent elective surgical excision, and there were no complications. Definitive pathological examination showed a metaplastic benign Brenner tumor.

Conclusion: The largest benign Brenner tumors reported in literature have been up to 30 cm in size, and greater size has been thought to be a predictor of malignancy. We have seen, however, that it is possible for larger lesions of this type to have a completely benign behavior; consequently, a benign nature should not be excluded even in the event of a large ovarian lesion.

Publication types

  • Case Reports

MeSH terms

  • Brenner Tumor / diagnostic imaging
  • Brenner Tumor / pathology*
  • Brenner Tumor / surgery
  • Female
  • Humans
  • Middle Aged
  • Ovarian Neoplasms / diagnostic imaging
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Tomography, X-Ray Computed
  • Tumor Burden