Encephalitozoon cuniculi genotype I as a causative agent of brain abscess in an immunocompetent patient

J Clin Microbiol. 2011 Jul;49(7):2769-71. doi: 10.1128/JCM.00620-11. Epub 2011 May 18.

Abstract

A brain abscess caused by Encephalitozoon cuniculi genotype I together with Streptococcus intermedius occurred in a patient without major immunocompromise and with diabetes. The distinguishing clinical signs were hemiparesis and epilepsy. The microsporidium was observed in the abscess aspirate, and its specific DNA was also detected in stool and urine. The patient was successfully treated with albendazole and mebendazole.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain / diagnostic imaging
  • Brain / pathology
  • Brain Abscess / diagnosis*
  • Brain Abscess / microbiology
  • Brain Abscess / pathology*
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Encephalitozoon cuniculi / classification*
  • Encephalitozoon cuniculi / genetics
  • Encephalitozoon cuniculi / isolation & purification*
  • Encephalitozoonosis / diagnosis*
  • Encephalitozoonosis / microbiology
  • Encephalitozoonosis / pathology*
  • Epilepsy / diagnosis
  • Epilepsy / etiology
  • Genotype
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Paresis / diagnosis
  • Paresis / etiology
  • Phylogeny
  • Radiography
  • Sequence Analysis, DNA
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / pathology
  • Streptococcus intermedius / isolation & purification

Substances

  • DNA, Fungal
  • DNA, Ribosomal Spacer

Associated data

  • GENBANK/GU198946
  • GENBANK/GU198947
  • GENBANK/GU198948