Complexation of terpyridine-containing dextrans: toward water-soluble supramolecular structures

Andreas Wild; Stephanie Hornig; Florian Schlütter; Jürgen Vitz; Christian Friebe; Martin D Hager; Andreas Winter; Ulrich S Schubert

doi:10.1002/marc.201000010

Complexation of terpyridine-containing dextrans: toward water-soluble supramolecular structures

Macromol Rapid Commun. 2010 May 12;31(9-10):921-7. doi: 10.1002/marc.201000010. Epub 2010 Apr 21.

Authors

Andreas Wild¹, Stephanie Hornig, Florian Schlütter, Jürgen Vitz, Christian Friebe, Martin D Hager, Andreas Winter, Ulrich S Schubert

Affiliation

¹ Laboratory of Organic and Macromolecular Chemistry, Friedrich-Schiller-University Jena, Humboldtstr.10, D-07743 Jena, Germany; Dutch Polymer Institute (DPI), P.O. Box 902, 5600 AX Eindhoven, The Netherlands.

PMID: 21590989
DOI: 10.1002/marc.201000010

Abstract

Dextran was functionalized with 6-(2,2':6',2″-terpyridin-4'-yloxy)-hexanoic acid using two different ratios of terpyridine to dextran, leading to terpyridine-functionalized dextran esters possessing different degrees of substitution (DS = 0.23-0.41). The intra- and intermolecular complexation behavior of both functionalized biopolymers was studied using Fe(II) metal ions as well as activated Ru(III) complexes. The complexation behavior in the first case was studied by UV-visible and viscosity titration experiments. In the latter case, a water soluble comb-polymer could be obtained when using a PEG- functionalized terpyridine Ru(II) moiety for complexation. Moreover, nanoprecipitation was applied to self-assemble the functionalized dextrans into nanoparticles.