In the title compound, C(32)H(38)N(3)O(6)S(2), an inter-mediate in the synthesis of polyamine drugs, the dihedral angle between the phenyl rings of the two 2,4,6-trimethyl-benzene-sulfonyl groups is 27.1 (3)°. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯O hydrogen bonds, thereby forming an infinite one-dimensional chain propagating along [010].