Pharmacokinetic monitoring of antiepileptic drugs

A Aldaz; R Ferriols; D Aumente; M V Calvo; M R Farre; B García; R Marqués; P Mas; B Porta; M Outeda; D Soy; Grupo PK-gen de la Sociedad Española de Farmacia Hospitalaria

doi:10.1016/j.farma.2010.10.005

Pharmacokinetic monitoring of antiepileptic drugs

Farm Hosp. 2011 Nov-Dec;35(6):326-39. doi: 10.1016/j.farma.2010.10.005. Epub 2011 May 13.

[Article in English, Spanish]

Authors

A Aldaz¹, R Ferriols, D Aumente, M V Calvo, M R Farre, B García, R Marqués, P Mas, B Porta, M Outeda, D Soy; Grupo PK-gen de la Sociedad Española de Farmacia Hospitalaria

Affiliation

¹ Servicio de Farmacia, Clínica Universitaria, Pamplona, España.

PMID: 21570885
DOI: 10.1016/j.farma.2010.10.005

Abstract

Monitoring plasma levels of antiepileptic drugs for the treatment and prophylaxis of epilepsy is one of the strategies enabling clinical results to improve by reducing adverse affects and increasing effectiveness. The objective of this article is to review the basic aspects in the monitoring of antiepileptic drugs using a consensus document prepared and endorsed by the pharmacokinetics and pharmacogenetics working group (PK.gen) of the Sociedad Española de Farmacia Hospitalaria (Spanish Society of Hospital Pharmacists).

Publication types

Review

MeSH terms

Anticonvulsants / blood
Anticonvulsants / pharmacokinetics*
Anticonvulsants / therapeutic use*
Consensus Development Conferences as Topic
Drug Monitoring / standards*
Epilepsy / blood
Epilepsy / drug therapy*
Humans

Substances

Anticonvulsants