Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine

ChemMedChem. 2011 Jul 4;6(7):1203-6. doi: 10.1002/cmdc.201100125. Epub 2011 May 12.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amidines / chemistry*
  • Amidines / pharmacology
  • Binding Sites
  • Catalytic Domain
  • Computer Simulation
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Nitric Oxide Synthase Type II / antagonists & inhibitors*
  • Nitric Oxide Synthase Type II / metabolism
  • Structure-Activity Relationship

Substances

  • Amidines
  • Enzyme Inhibitors
  • W1400
  • Nitric Oxide Synthase Type II
  • acetamidine