Boron neutron capture therapy combined with fractionated photon irradiation for glioblastoma: a recursive partitioning analysis of BNCT patients

K Nakai; T Yamamoto; H Aiyama; T Takada; F Yoshida; T Kageji; H Kumada; T Isobe; K Endo; M Matsuda; T Tsurubuchi; Y Shibata; S Takano; M Mizumoto; K Tsuboi; A Matsumura

doi:10.1016/j.apradiso.2011.03.049

Boron neutron capture therapy combined with fractionated photon irradiation for glioblastoma: a recursive partitioning analysis of BNCT patients

Appl Radiat Isot. 2011 Dec;69(12):1790-2. doi: 10.1016/j.apradiso.2011.03.049. Epub 2011 May 5.

Authors

K Nakai¹, T Yamamoto, H Aiyama, T Takada, F Yoshida, T Kageji, H Kumada, T Isobe, K Endo, M Matsuda, T Tsurubuchi, Y Shibata, S Takano, M Mizumoto, K Tsuboi, A Matsumura

Affiliation

¹ Department of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, Tennodai, Tsukuba, Japan. knakai@Neurosurg-tsukuba.com

PMID: 21565517
DOI: 10.1016/j.apradiso.2011.03.049

Abstract

Eight patients to received Boron Neuron Capture Therapy (BNCT) were selected from 33 newly diagnosed glioblastoma patients (NCT(+) group). Serial 42 glioblastoma patients (NCT(-) group) were treated without BNCT. The median OS of the NCT(+) group and NCT (-) group were 24.4 months and 14.9 months. In the high risk patients (RPA class V), the median OS of the NCT(+) group tended to be better than that of NCT(-) group. 50% of BNCT patients were RPA class V.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Boron Neutron Capture Therapy*
Brain Neoplasms / radiotherapy*
Female
Glioblastoma / radiotherapy*
Humans
Male
Middle Aged
Photons*
Survival Analysis